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Breakthrough Pig Kidney Transplant in Brain-Dead Patient Marks Revolutionary Step in Organ Transplantation

Breakthrough Pig Kidney Transplant in Brain-Dead Patient Marks Revolutionary Step in Organ Transplantation
Published 2 years ago on Aug 17, 2023

In a remarkable medical feat, surgeons at NYU Langone Health have achieved a milestone by successfully transplanting a pig kidney into a brain-dead man, who has now sustained on the organ for over a month. This pioneering procedure is being hailed as a potential game-changer in the realm of organ transplantation, offering hope for a sustainable solution to the scarcity of donor organs.

Pig kidneys transplants could one day become a life-saving medical procedure, the team at NYU says.

Promising Medical Breakthrough: NYU Langone Health announced a medical triumph as they managed to keep a gene-edited pig kidney functioning within a human recipient for an unprecedented duration. This achievement is a significant step forward towards establishing a reliable and alternative supply of organs for transplantation, addressing the perennial issue of organ shortage.

Gratitude for a Selfless Contribution: Special acknowledgment was extended to Mary Miller Duffy, the sister of the brain-dead individual, Maurice Miller, for her selfless decision to allow her brother's body to be used for this pioneering procedure. Dr. Robert Montgomery, the lead surgeon and chair of the NYU Langone Health Department of Surgery, expressed immense gratitude to Mary for her courageous and compassionate act, which allowed her brother to contribute to medical advancements even after his passing.

Innovative Procedure and Ongoing Research: The groundbreaking surgery, conducted on July 14, involved a unique approach to cross-species organ transplantation, known as xenotransplantation. The pig kidney, modified with a single genetic alteration and devoid of experimental interventions, was integrated into the patient's circulatory system. The transplant was facilitated by "knocking out" the alpha-gal gene and positioning the pig's thymus gland underneath the kidney's outer layer to prevent immune responses.

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In a remarkable medical feat, surgeons at NYU Langone Health have achieved a milestone by successfully transplanting a pig kidney into a brain-dead man, who has now sustained on the organ for over a month. This pioneering procedure is being hailed as a potential game-changer in the realm of organ transplantation, offering hope for a sustainable solution to the scarcity of donor organs.

Pig kidneys transplants could one day become a life-saving medical procedure, the team at NYU says.

Promising Medical Breakthrough: NYU Langone Health announced a medical triumph as they managed to keep a gene-edited pig kidney functioning within a human recipient for an unprecedented duration. This achievement is a significant step forward towards establishing a reliable and alternative supply of organs for transplantation, addressing the perennial issue of organ shortage.

Gratitude for a Selfless Contribution: Special acknowledgment was extended to Mary Miller Duffy, the sister of the brain-dead individual, Maurice Miller, for her selfless decision to allow her brother's body to be used for this pioneering procedure. Dr. Robert Montgomery, the lead surgeon and chair of the NYU Langone Health Department of Surgery, expressed immense gratitude to Mary for her courageous and compassionate act, which allowed her brother to contribute to medical advancements even after his passing.

Innovative Procedure and Ongoing Research: The groundbreaking surgery, conducted on July 14, involved a unique approach to cross-species organ transplantation, known as xenotransplantation. The pig kidney, modified with a single genetic alteration and devoid of experimental interventions, was integrated into the patient's circulatory system. The transplant was facilitated by "knocking out" the alpha-gal gene and positioning the pig's thymus gland underneath the kidney's outer layer to prevent immune responses.

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